Multi-level caching

Give a brief description of Multi-level caching scenarios. E.g. when to use it, and how?
    
    Multi level cache means a situation where we use more than one caching methods e.g. on the server side we can use memchache or Varnish or we can cache pages too (caching both on the PHP and SQL sides).
    
    A  multilevel cache spreads the cached data contents across several servers across the network.
    1. The top level caching server holds the most commonly accessed pages, and the lowest-level caching server holds the least commonly accessed pages.
    2. The various levels combine in a network of cache servers called a Web caching mesh.
    3. The caches communicate among themselves, using HTTP and special cache-coordination protocols, to divide the contents appropriately and maintain consistency among the servers.

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